Correlation between carbohydrate, protein and fat intake with serum c-reactive protein level in lung cancer patients stage IIIB-IV

  • Patricia Amanda Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital
  • Diana Sunardi Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital
  • Noorwati Sutandyo Faculty of Medicine, Universitas Indonesia
Keywords: C-Reactive Protein, inflammation, lung cancer, carbohydrate intake, protein intake and fat intake.

Abstract

Introduction: The aim of the study is to determine the correlation between carbohydrate, fat and protein intake with the serum C-Reactive Protein level in lung cancer patients stage IIIB IV. The progression of lung cancer is influenced by immune system, genetic factors and inflammatory response, therefore CRP can be relied as one of the parameters for predicting cancer cell growth.Methods: The research with cross sectional design was conducted in Dharmais Cancer Hospital Jakarta. Subjects were recruited by consecutive sampling, 49 subjects with lung cancer stage IIIB- IV who currently not receving any treatment in Dharmais Hospital participating in this study A total of 49 subjects with lung cancer stage IIIB- IV who currently not receving any treatment were taken using consecutive sampling method. Results: The mean age of subject was 55,82 + 12,26 years old and 63,3% were male. The median value of CRP is 23,82 (0,30 - 207,29) mg/L.Conclusion: This study did not showed significant correlation between carbohydate, protein and fat intake with serum CRP level (p = 0,919; p = 0,257; p = 0,986, respectively). But on additional analysis we did found that there was a negative, non significant correlation between protein intake and serum CRP level in cancer patient stage IV, as well as fat intake and serum CRP level.