Body Mass Index And Survival Rate in Nasopharyngeal Cancer Patient: An Evidence-based Case Report

Yohannessa Wulandari, Metta Satyani, Marvin Marino, Nurul Ratna Mutu Manikam


Introduction: Nasopharyngeal cancer is the most common type of head and neck cancer with prevalence of 6.2/100000 population. Recently, study of prognostic factors for nasopharyngeal cancer still becomes one of research focuses. Several studies have tried to find the relationship between nutritional status (body mass index/BMI) and nasopharyngeal cancer patients’ survival rate, but the results are still inconsistent.                    

Objective: To find the relationship between nutritional status represented by BMI and nasopharyngeal cancer patients’ survival rate.

Methods: Electronic literature searches were performed in Cochrane®, Scopus®, and Pubmed®. Mesh term and title/abstracts were screened based on inclusion and exclusion criteria before relevant journals were reviewed.

Results: Two articles were selected based on the eligibility criteria and relevancy to the clinical question. In the study of Huang et al., the subject was nasopharyngeal cancer patient stage III and IV was included as subject of the study. In the study of Lin et al., nasopharyngeal cancer patient with metastases was also included. Patient with higher BMI has better survival rate than underweight BMI category.

Conclusion: Increasing BMI in underweight cancer patient simproves nasopharyngeal cancer patient’ survival rate.


nasopharyngeal cancer; nasopharyngeal neoplasm; body mass index; BMI; survival rate; prognosis

Full Text:



Thompson LDR. Head and Neck Cancers. In: Stewart BW, Wild CP, eds. World Cancer Report 2014. France: International Agency for Research on Cancer; 2014. [Google Scholar]

Adham M, Kurniawan AN, Muhtadi AI, Roezin A, Hermani B, Gondhowiardjo S, et al. Nasopharyngeal carcinoma in Indonesia: epidemiology, incidence, signs, and symptoms at presentation. Chinese journal of cancer 2012;31(4):185. [Google Scholar]

Bradley PJ. Head and Neck Cancer. In: Ludman H, Bradley PJ, eds. ABC of Ear, Nose and Throat. 6 ed. USA: Wiley-Blackwell; 2013. [Google Scholar]

Vokes EE. Head and Neck Cancer. In: Kasper DL, Hauser SL, Jameson JL, Fauci AS, Longo DL, Loscalzo J, eds. Harrison's Principles of Internal Medicine. 19 ed: McGraw-Hill; 2015. [Google Scholar]

Lin JC. Prognostic Factors in Nasopharyngeal. Berlin: Springer; 2010. [Google Scholar]

Huang PY, Wang CT, Cao KJ, Guo X, Guo L, Mo HY, et al. Pretreatment body mass index as an independent prognostic factor in patients with locoregionally advanced nasopharyngeal carcinoma treated with chemoradiotherapy: Findings from a randomised trial. European Journal of Cancer 2013;49:1923-31. [Google Scholar]

Critical Appraisal of Prognostic Studies. Centre for Evidence-Based Medicine University of Oxford. at

Li W, Shen LJ, Chen T, Sun XQ, Zhang Y, Wu M, et al. Overweight/obese status associates with favorable outcome in patients with metastatic nasopharyngeal carcinoma: a 10-year retrospective study. Chinese journal of cancer 2016;35:75. [Google Scholar]

Howick J, Chalmers I, Glasziou P, Greenhalgh T, Heneghan C, Liberati A, et al. Oxford Centre for Evidence-Based Medicine 2011 Levels of Evidence. Oxford Centre for Evidence-Based Medicine 2011.



  • There are currently no refbacks.

Copyright (c) 2020 Yohannessa Wulandari, Metta Satyani, Marvin Marino, Nurul Ratna Mutu Manikam

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

View My Stats