Early-menarche as Determinant Factor for Metabolic-risks: An Epidemiology Perspectives among Adolescent Girls aged 13-15 years old in Jakarta-Indonesia

Ririn Hariani, Vikie Nouvrisia, Dhevinia Yustikarani, Saptawati Bardosono, Noorwati Sutandyo

Abstract


Background and Objectives:

Early menarche predicts higher body mass index (BMI) and adiposity in adult life, and it has been associated with risk factors of cardiometabolic diseases such as elevated triglycerides and waist circumferences also higher risk of adult diabetes. This study aims to explore early-menarche as determinant factor for metabolic-risks among adolescent girls aged 13-15 years old.

Methods and Study Design:

This cross-sectional study was undertaken in adolescent girls aged 13-15 years in all five municipalities in Jakarta-Indonesia, from January 2014 to Mei 2016. Data collected by using standardized measures for dietary intake, nutritional status indicators, physical activity level, blood pressure, blood glucose and lipid profile, and statistically analyzed by independent-t or Mann-Whitney test, and Pearson or Spearman correlation test.

Results and Conclusions:

A total of 194 adolescent girls were participated in this study. Early menarche was found in 22.68% of all subjects. There was no association between menarche status and daily macronutrients intake pattern and physical activity level score. Early menarche subjects had significantly higher BMI (p<0.001), CDC-percentile (p<0.001), WHO Z-score (p<0.001), and waist circumference values (p=0.02). Furthermore, early menarche subjects also had higher systolic blood pressure (p=0.035), total cholesterol level (p=0.028), LDL-cholesterol level (p=0.013), and triglyceride level (p=0.026). There was no association between menarche status and diastolic blood pressure, fasting blood glucose, HDL-C level, lipid profile ratio. In conclusion, early menarche is an important determinant factor of metabolic risks, and balance between dietary intake and physical activity level should be prioritized among them.


Keywords


adolescent girls, metabolic risks, dietary intake, nutritional status indicators

References


Batubara JRL. Adolescent development (perkembangan remaja). Sari Pediatri. 2010;12: 21-9.

Karapanou O, Papadimitriou A. Determinant of Menarch. Reproductive Biology and Endocrinology. 2010;8: 115

Save the Children. Adolescent Nutrition Policy and Programming in SUN+ Countries. London: NXP Europe Ltd; 2015. p. 48

Branca F, Piwoz E, Schultink W, Sullivan LM. Nutrition and health in women, children, and adolescent girls. BMJ. 2015;351: 2731

Mounir GM, El-Sayed NA, Mahdy NH, Khamis SE. Nutritional Factors Affecting the Menarcheal State of Adolescent School Girls in Alexandria. J Egypt Public Health Assoc. 2007;82(3&4): 23960

Juliyatmi RH, Handayani L. Nutritional Status and Age at Menarche on Female Students of Junior High School. International Journal of Evaluation and Research in Education. 2015;4(2): 71 5

Stang J. Adolescent nutrition. In: Brown JE, editor. Nutrition through life cycle 4th ed. Belmont: Wadsworth; 2011. p. 357-84.

Schnabel RB. Is It All Determined at Menarche?. Circulation. 2015;131:227-9.

Mueller NT, Duncan BB, Barreto SM, Chor D, Bessel M Aquino EML, Pereira MA, et al. Earlier age at menarche is associated with higher diabetes risk and cardiometabolic disease risk factors in Brazilian adults: Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Cardiovascular Diabetology. 2014;13(22):18.

Hariani R. Faktor Determinan Kadar Estradiol dan Menarche Dini pada Remaja Putri Usia 13-15 Tahun di Jakarta. (dissertation). Jakarta: Universitas Indonesia, 2015.

Susanti AV, Sunarto. Faktor risiko kejadian menarche dini pada remaja di SMPN 30 Semarang. J Nutr College. 2012;1:386-407.

Cho GJ, Park HT, Shin JH, Hur JY, Kim YT, Kim SH, et all. Age at menarche in Korean population: Secular trends and influencing factors. Eur J Pediatr. 2010;169:89-94.

Dreyfus J. Early Pubertal Development and Cardiometabolic Risk: a Life Course Approach. (dissertation). Minnesota: The University of Minnesota, 2013.

Dreyfus J, Jacobs DR, Mueller N, Schreiner PJ, Moran A, Carnethon MR, Demerath EW. Age at menarche and cardiometabolic risk in adulthood: the Coronary Artery Risk Development in Young Adults Study. J Pediatr. 2015;167(2):34452.

Won JC, Hong JW, Noh JH, Kim DJ. Association Between Age at Menarche and Risk Factors for Cardiovascular Diseases in Korean Women. The 2010 to 2013 Korea National Health and Nutrition Examination Survey. Medicine. 2016;95(18):1-7.

Chan NPT, Choi KC, Nelson EAS, Chan JC, Kong APS. Associations of pubertal stage and body mass index with cardiometabolic risk in Hong Kong Chinese children: A cross-sectional study. BMC Pediatrics. 2015;15:136.

De Ridder CM, Thisjssen JHH, Veer PV, Duuren RV, Brunning PF, Zonderland ML, et al. Dietary habits, sexual maturation, and plasma hormones in pubertal girls: a longitudinal study. Am J Clin Nutr. 1991;54:805-13.

Moisan J, Meyer F, Gingras S. Diet and age at menarche. Cancer Causes Control. 1991;1:149-154.

Schimdt TJ, Litwack G. Biochemistry of Hormones. In: Textbook of Biochemistry with Clinical Correlation. 6th ed. Canada:Wiley-Liss Publication. 2006. p.892-942.

Wen X, Li D, Tozer AJ, Docherty SM, Iles RK. Estradiol, progesterone, testosterone profiles in human follicular fluid cultured granulose cells from luteinized pre-ovulatory follicles. Reprod Biol Endocrinol. 2010;8:117-26.

Simpson ER. Sources of estrogen and their importance. J Steroid Biochem Mol Biol. 2003;86:225-30.

Maclure M, Travis LB, Willet W, MacMahon B. A prospective cohort study of nutrient intake and age at menarche. Am J Clin Nutr. 1991;54:649-56.

Canoy D, Beral V, Balkwill A, Wright FL,. Kroll ME, Reeves GK, Green J, Cairns BJ. Age at Menarche and Risks of Coronary Heart and Other Vascular Diseases in a Large UK Cohort. Circulation. 2014;131:237-44.

Lai TC, Leung GM, Schooling CM. Maternal Age of Menarche and Blood Pressure in Adolescence: Evidence from Hong Kongs Children of 1997 Birth Cohort. PLoS ONE 11(7):1-10.

Baek TH, Lim NK, Kim MJ, Lee J, Ryu S, Chang Y, Choi Y, Park HY. Age at menarche and its association with dysglycemia in Korean middle-aged women. Menopause. 2015; 22(5):542-8.

Teixeira FC, Pereira FEF, Pereira AF, Ribeiro BG. Metabolic syndromes risk factors and its association with nutritional status in schoolchildren. Preventive Medicine Reports. 2017;6:27-32.

Pietrobelli A, Lee RC, Capristo E, Deckelbaum RJ, Heymsfield SB. An independent, inverse association of high-density-lipoproteincholesterol concentration with nonadipose body mass. Am J Clin Nutr. 1999;69:61420.

Lima SCVC, Lyra CO, Pinheiro LGB, Azevedo PRM, Arrais RF, and Pedrosa LFC. Association between dyslipidemia and anthropometric indicators in adolescents. Nutr Hosp. 2011;26(2):304-10.

Meral G, Uslu A, Yozgatli AU, Akay F. Association of Body Mass Index and Lipid Profiles in Children. Open Journal of Pediatrics. 2015;5:141-6.

Di Bonito P, Moio N, Scilla C, Cavuto L, Sibilio G, Sanguigno E, et al. Usefulness of the High Triglyceride-to-HDL Cholesterol Ratio to Identify Cardiometabolic Risk Factors and Preclinical Signs of Organ Damage in Outpatient Children. Diabetes Care. 2012;35:158-162.

Chavez AG, Mendia LES, Arguetta SE. Elevated triglycerides/HDL-cholesterol ratio associated with insulin resistance. Cir Cir. 2011;79:115-9.

Weiss R, Otvos JD, Sinnreich R, Miserez AR, Kark JD. The triglyceride to high-density lipoprotein-cholesterol ratio in adolescence and subsequent weight gain predict nuclear magnetic resonance-measured lipoprotein subclasses in adulthood. J Pediatr 2011;158:4450.

Rodriguez G, Moreno LA, Blay MG, Blay VA, Garagorri JM, Sarria A, Bueno M. Body composition in adolescents: measurements and metabolic aspects. Intenational Journal of Obesity 2004;28:S54-S58.

Ventura AK, Loken E, Birch LL. Risk Profiles for Metabolic Syndrome in a Nonclinical Sample of adolescent Girls. Pediatrics 2006;118(6):24342442.




DOI: https://doi.org/10.25220/WNJ.V01i2.0010

Refbacks

  • There are currently no refbacks.


Copyright (c) 2018 Ririn Hariani, Vikie Nouvrisia, Dhevinia Yustikarani, Saptawati Bardosono, Noorwati Sutandyo

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

View My Stats