Correlation between serum vitamin C level and COPD assessment test score in chronic obstructive pulmonary disease patients

Main Article Content

Cipuk Muhaswitri
Drupadi Dillon
Jamal Zaini


Background: COPD is a disease due to oxidative stress causing low pulmonary function, resulting in low quality of life. A standard test to measure the quality of life in COPD is COPD Assessment Test (CAT). Vitamin C as antioxidant is widely available in the pulmonary epithelial fluid.  This study aimed to investigate the correlation between serum vitamin C level and CAT score in COPD.Methods: This cross-sectional study was conducted at Persahabatan Hospital, East Jakarta, involving 47 subjects using consecutive sampling method. Interview was used to assess subjects’ characteristics and vitamin C intake using semi-quantitative FFQ. Clinical classification, lung function, comorbidity, and CAT scores were gathered from medical records or interview. BMI was used to determine nutritional status, while vitamin C serum level was assessed using spectrophotometry. Results and conclusions: All subjects were male, mean age was 66.6 years, mostly ex-heavy  smokers, with decreased lung function, and 25% were undernourished. Vitamin C intake was sufficient, but low in serum vitamin C level and CAT score.There was no correlation between serum vitamin C level and CAT score.


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Author Biographies

Cipuk Muhaswitri, Universitas Indonesia, Cipto Mangunkusumo General Hospital

Department of Nutrition Medical Faculty Universitas Indonesia

Drupadi Dillon, Universitas Indonesia, Cipto Mangunkusumo General Hospital

Department of Nutrition Medical Faculty Universitas Indonesia

Jamal Zaini, Universitas Indonesia, Cipto Mangunkusumo General Hospital

Departement of Pulmonology and Respiratory Medicine, Persahabatan General Hospital


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