The impact of prebiotic, probiotic, and synbiotic supplements on CD4, CD8 counts and inflammatory markers in HIV patients: A systematic review and meta-analysis

Josephine Claudia  Sirait; A.A. Sagung Mirah  Prabandari; M. Candra  Wijanadi; Agustinus Wayan  Harimawan; I Wayan Gede  Sutadarma

doi:10.25220/WNJ.V08.S1.0023

The impact of prebiotic, probiotic, and synbiotic supplements on CD4, CD8 counts and inflammatory markers in HIV patients: A systematic review and meta-analysis

Josephine Claudia Sirait
A.A. Sagung Mirah Prabandari Udayana University, Ngoerah Hospital, Denpasar, Bali
M. Candra Wijanadi Department Udayana University, Ngoerah Hospital, Denpasar, Bali
Agustinus Wayan Harimawan Department Udayana University, Ngoerah Hospital, Denpasar, Bali
I Wayan Gede Sutadarma Udayana University, Ngoerah Hospital, Denpasar, Bali

DOI: https://doi.org/10.25220/WNJ.V08.S1.0023

Keywords: probiotic, prebiotic, symbiotic, CD4, inflammatory markers

Abstract

HIV infection compromises immune function and depletes CD4+ T-lymphocytes. Prebiotics, probiotics, and synbiotics are potential dietary supplements to improve immune status and manage inflammation in HIV patients. This systematic review and meta-analysis investigated their effects on CD4 count, CD8 count, and inflammatory markers in HIV patients.